منابع مشابه
Experimental Analysis of Crashworthiness Behavior of Energy Absorber Tubes Under 3D Oblique Load
Actual applications of the energy absorbers showed that actual loads are not applied in the form of pure axial compression, pure bending or pure torsion. In reality, an energy absorber component may be subjected to combined loading of compression, bending and torsion. A number of previous articles have investigated the behavior of energy absorbers under oblique loading. In such cases, the obliq...
متن کاملThe Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load
The response of motor proteins to external loads underlies their ability to work in teams and determines the net speed and directionality of cargo transport. The mammalian kinesin-2, KIF3A/B, is a heterotrimeric motor involved in intraflagellar transport and vesicle motility in neurons. Bidirectional cargo transport is known to result from the opposing activities of KIF3A/B and dynein bound to ...
متن کاملFlexibility of the neck domain enhances Kinesin-1 motility under load.
Kinesin-1 is a dimeric motor protein that moves stepwise along microtubules. A two-stranded alpha-helical coiled-coil formed by the neck domain links the two heads of the molecule, and forces the motor heads to alternate. By exchanging the particularly soft neck region of the conventional kinesin from the fungus Neurospora crassa with an artificial, highly stable coiled-coil we investigated how...
متن کاملBackstepping H∞ Control for Switched Nonlinear Systems under Arbitrary Switchings
This paper is concerned with the global H∞ control problem for a class of switched nonlinear systems in lower triangular form under arbitrary switchings. A common Lyapunov function and a common smooth state feedback controller are constructed by backstepping such that the closedloop system is globally asymptotically stable under arbitrary switchings without disturbance input and has the prescri...
متن کاملDirect Long-Term Observation of Kinesin Processivity at Low Load
The hand-over-hand stepping mechanism of kinesin at low loads is inadequately understood because the number of molecular steps taken per encounter with the microtubule is difficult to measure: optical traps do not register steps at zero load, while evanescent wave microscopy of single molecules of GFP-kinesin suffers from premature photobleaching. Obtaining low-load data is important because it...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.233